Whether your dog trembles during thunderstorms, panics when left alone, or turns into a nervous wreck at the vet, calming treats can make a real difference. The best calming treats for dogs use natural ingredients like chamomile, L-theanine, and melatonin to take the edge off without sedating your pup. We tested and reviewed the top options on the market to help you find the right fit.
How Do Calming Treats Work?
Calming treats use natural compounds that interact with your dog’s nervous system to reduce stress. L-theanine, an amino acid found in green tea, promotes relaxation by increasing serotonin and dopamine. Chamomile has mild sedative properties that calm the nervous system. Valerian root works similarly to chamomile and helps with sleep. Melatonin regulates the sleep-wake cycle and can help dogs who get anxious at night.
These treats are not sedatives — they won’t knock your dog out. Instead, they help bring anxiety levels down to a manageable level so your dog can cope with stressful situations more calmly.
Our Top 5 Picks for 2026
1. Zesty Paws Calming Bites
These chicken-flavored soft chews contain Suntheanine (a pure form of L-theanine), organic chamomile, valerian root, and organic passionflower. They’re one of the most popular calming treats on Amazon for good reason — most dogs love the taste, and owners report noticeable results within 30 to 60 minutes.
2. VetriScience Composure Pro
A veterinarian-formulated option that uses Colostrum Calming Complex, L-theanine, and thiamine. It’s fast-acting and comes in bite-sized chews that work well for situational anxiety like vet visits or car rides. Many vets recommend this brand specifically.
3. PetHonesty Hemp Calming Chews
These combine hemp seed powder with chamomile, valerian root, and ginger root. The addition of ginger makes them a great option for dogs with travel-related nausea and anxiety. They’re made in the USA with no artificial preservatives.
4. NaturVet Quiet Moments
An affordable everyday option that uses chamomile, thiamine, passionflower, and melatonin. Particularly effective for nighttime anxiety and helping dogs settle down for sleep. Available in soft chew and tablet form.
5. Purina Pro Plan Calming Care
A probiotic supplement rather than a traditional treat, this uses a specific strain of beneficial bacteria (BL999) clinically shown to help dogs maintain calm behavior. It takes about 6 weeks to reach full effectiveness but delivers lasting results.
When to Use Calming Treats vs. Medication
The best calming treats for dogs work well for mild to moderate anxiety — thunderstorms, fireworks, travel, grooming, or mild separation anxiety. However, if your dog’s anxiety is severe — destructive behavior, self-harm, refusal to eat, or constant panting and pacing — calming treats alone probably won’t be enough.
In those cases, talk to your veterinarian about prescription options. Calming treats can still be used alongside medication as part of a comprehensive anxiety management plan.
Frequently Asked Questions
Q: How long do calming treats take to work?
A: Most calming treats take 30 to 60 minutes to take effect. Give them to your dog before the stressful event, not during it.
Q: Can I give my dog calming treats every day?
A: Most products are safe for daily use. Check the label for dosage instructions specific to your dog’s weight.
Q: Do calming treats make dogs drowsy?
A: Most calming treats promote relaxation without sedation. Melatonin-based treats may cause mild drowsiness, which can be helpful for nighttime anxiety.
Q: Are calming treats safe for puppies?
A: Check the product label — most calming treats are designed for dogs over 12 weeks old. Consult your vet for very young puppies.
